July 27, 2013

Hunger-Stimulating FTO Gene

1 Researchers Identify Genetic Obesity Cause

There may be a genetic reason why some people are more inclined to overeat and become obese: a variant of the FTO gene which controls certain enzymes. People who carry two copies of this particular variant have much higher levels of ghrelin, a hunger-stimulating hormone, even after eating, and are more attracted to high-calorie food than those with other FTO versions, creating what one researcher called "a double hit" on the ability to resist eating. Roughly one in six people carry two copies of the FTO variant and are 70 percent more likely to be obese than those without it, but they are not necessarily doomed to obesity, since extra ghrelin can be reduced by exercise or eating a high-protein diet, and people with the variant weigh just 6.5 pounds more on average than non-carriers.

More at Webmd.com | Posted 4 years ago by Robert S. Wieder

Previously: Gene Linked to Obesity May Lead to Dementia

Tags: Causes of Obesity, Genes and Obesity, Genetic Causes of Obesity, Genes and Hunger, FTO Gene, FTO Variant

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