July 6, 2012

In Older Americans

1 High Doses of Vitamin D Reduce Fracture Risk

Higher doses of vitamin D reduce the risk of fracture in older adults find Tufts University researchers who analyzed clinical trials that investigated vitamin D supplementation in 31000 older adults. Researchers divided the subjects into groups based on their vitamin D intake - between 0 and 2000 IUs/day - and found that those taking the highest daily doses - between 800 and 2000 IUs - had 30% fewer hip fractures and 14% fewer fractures of other bones compared to those in the study’s control groups. Researchers also found that there was no benefit in taking vitamin D in doses below 800 IUs/day for fracture prevention. The current Dietary Reference Intake for vitamin D in older adults is a minimum of 600 IUs/day for adults ages 51-70 and 800 IUs for adults 70+.

More at ScienceDaily.com | Posted 5 years ago by Melody Lesser

Previously: Dietary Protein Helps Prevent Hip Fractures

Tags: Fractures, Hip Fractures, Tufts University, Vitamin D, Fractures in Older Adults

Comment on This | Was this Interesting? Yes! (45%) / No! (55%)

Metformin on the Mind

2 Diabetes Drug Metformin Makes New Brain Cells

New research in mice has found that they type 2 diabetes drug metformin promotes the growth of new neurons in the brain. The PKC-CBP pathway the drug uses in liver cells to help diabetics control their glucose is the same one that directs neural stems to differentiate into adult neurons and it was this pathway that led researchers to conduct this study. Not only did they make more neurons, but their spatial learning, determined by having them finding a hidden platform in a maze was better compared to the control group. There is some evidence that metformin alleviates Alzheimer’s symptoms and because it is commonly used and safe, researchers hope that the drug can be tested in people to determine if it can repair brain damage due to trauma and radiation treatments to fight cancer.

More at Science Daily | Posted 5 years ago by Kristie Hayes

Previously: Metformin Fights Alzheimer’s in Mice

Tags: Brain Damage, Metformin, Neural Stem Cells, PCK-CBP Pathway

Comment on This | Was this Interesting? Yes! (59%) / No! (41%)

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