December 10, 2011

Drospirenone May Raise VTE Risk

1 FDA Calls for New Label on Yaz

Labels on oral contraceptives like Yaz may not adequately inform patients of the risk-benefit profile involved, voted FDA advisers. Birth control pills that contain drospirenone rather than the hormone progestin could raise the risk of venous thromboembolism (VTE), but more study is needed. VTE is a dangerous condition involving blood clots that can possibly move around inside the circulatory system. Oral contraceptives with drospirenone include Yaz, Yasmin, Sayfral and Beyaz. CNN reports that most of the committee members think the benefits of the drugs outweigh the risks, but some members noted that other available birth control pills may have a lower risk of VTE.

More at CNN | Posted 6 years ago by Peggy Rowland

Previously: Birth Control Pills Erase the Details

Tags: Yaz Warning, Birth Control Dangers, Yaz Risks, Yasmin Warning, Beyaz Side Effects, Sayfral Label, Yaz Label, Venous Thromboembolism Risks, Venous Thromboembolism Caused Birth Control, Yaz VTE, Drospirenone Risks

Comment on This | Was this Interesting? Yes! (39%) / No! (61%)

Correction in Clotting

2 Gene Therapy Helps Those with Hemophilia B

A clinical trial involving six patients with hemophilia B shows that delivering the correct gene to the liver via a specially designed viral vector increases the production of clotting factor IX. People with the bleeding disorder either have a defective or missing gene and as a result they bleed more after a trauma than most people and even bleed spontaneously. Each patient received a different amount of the corrective gene. Four of them do not get the treatment regularly anymore and are no longer spontaneously bleeding and the other two are getting treated every 10-14 days as opposed to the initial regiment of two or three times a week. The results suggest the highest amount of gene should be given and researchers want to use the same technique to treat those with hemophilia A.

More at Yahoo! Reuters | Posted 6 years ago by Kristie Hayes

Previously: Hemophilia Drug Mostly Being Used off-Label

Tags: Gene Therapy, Hemophilia A, Hemophilia B, Bleeding Disorders, Clotting Factor IX, Viral Vector

Comment on This | Was this Interesting? Yes! (54%) / No! (46%)

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