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Blocks Cytokines Effects

Some T Cells Help Regenerate Stem Cells

A new study from the Center of Craniofacial Molecular Biology at the Ostrow School of Dentistry of University of Southern California has found that regulatory T cells ability to decrease the levels of the cytokines interferon (INF)-gamma and tumor necrosis factor (TNF)-alpha helped mice with bone defects to lay down new bone faster through bone marrow mesenchymal stem cells (BMMSC)-mediated bone regeneration and aspirin sped the process up. Most of the time, infection-fighting T cells secrete these cytokines which target and destroy stem cells and inhibit bone production. Now that the role of T-cells in tissue regeneration has been shown, researchers in the field of tissue regeneration are going to have to take into account the immune system’s role.

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