September 14, 2011

Get in the Zone

1 Talk Test Good Measure of Exercise Intensity

Is the Talk Test, a common measure of exercise intensity, accurate? U of New Hampshire researchers administered the Talk Test to healthy adults having them read aloud while working out at different levels of intensity and then rating how comfortable they were speaking. When exercising at the low end of established exercise intensity guidelines as measured by oxygen consumption and heart rate, participants said they could speak comfortably. The opposite is true when they worked out at the upper end of intensity guidelines. Researchers say the Talk Test is a useful tool. “If you can still talk comfortably, you’re exercising in a zone that’s appropriate for improving fitness” for beginners. If, however, “you really want to improve, you’ve got to push a little harder.”

More at ScienceDaily.com | Posted 6 years ago by Melody Lesser

Previously: Exercise, the Magic Drug for Depression

Tags: Aerobics, Exercise, Heart Rate, Exercise Intensity, Talk Test, University of New Hampshire, Oxygen Consumption

Comment on This | Was this Interesting? Yes! (41%) / No! (59%)

Intellectual Disabilities

2 Bachmann Uses Wrong Word: Retardation

Rep. Michele Bachmann of Minnesota, current Republican presidential hopeful, is in trouble for using the offensive words "mental retardation," and for tying the HPV vaccine with a risk that's not supported by scientific evidence. Bachmann told Matt Lauer that a mother approached her following the CNN Tea Party Debate to say that her daughter developed "mental retardation" following receiving the HPV vaccine. Rosa's law, enacted last year while Bachmann was active in Congress, took the words "mental retardation" out of use in social security, federal health and labor legislation. The replacement is “intellectual disability" or “intellectual developmental disabilities.”

More at MSNBC | Posted 6 years ago by Peggy Rowland

Previously: Congress Outlaws Use of Term Mental Retardation

Tags: Cervical Cancer Vaccine, Intellectual Disabilities, Mental Retardation, Offensive Language Disabilities, Michelle Bachmann HPV Vaccine

Read the Comments (1) | Was this Interesting? Yes! (53%) / No! (47%)

Kills Breast Cancer Stem Cells

3 Gene Therapy Plus Chemo Fights Breast Cancer

New research from the University of Texas MD Anderson Cancer Center has found that the gene BikDD kills breast cancer stem cells and increases chemotherapy’s effectiveness. It has been established that three proteins-Bcl-2 and Bcl-xL and Mcl1-promote their survival, growth and chemoresistance. By combining BikDD with claudin4 that expresses the gene in breast cancer cells which were delivered to the tumor via a versatile expression vector (VISA) increased the sensitivity of Her2 and EGFR+ breast cancer cell lines treated with lapatinib and paclitaxel. Mice that received VISA-claudin4-BikDD therapy had half the tumor volume compared to the control group and the treatment was very safe. It is very difficult to kill stem cells and they are believed to be the reason for relapse.

More at Science Daily | Posted 6 years ago by Kristie Hayes

Previously: Researchers Target Breast Cancer Stem Cells

Tags: Bcl-2, Breast Cancer Stem Cells, EGFR, Paclitaxel, Gene Therapy to Treat Breast Cancer, Versatile Expression Vector, Breast Cancer Resistance, Bcl-XL, Mcl1, BikDD, VISA-Claudin4-BikDD Therapy, Her2, Lapatinib, University of Texas MD Anderson Cancer Center

Read the Comments (1) | Was this Interesting? Yes! (47%) / No! (53%)

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