May 2, 2011

Higher BMIs and Obesity

1 Business Travel May Affect Health

People who travel more than 20 days per month are at higher risk for obesity, high cholesterol and an unhealthy BMI than those who travel one to six days per month. Researchers at Columbia U examined data from medical records of 13,000 people, the vast majority of whom traveled at least one night per month. Besides the health risks, those who travel extensively were more likely to rate their health as fair to poor than those whose travel is limited. Study authors say that road warriors should monitor their health and that, should further studies substantiate a link between business travel and metabolic diseases, workplace interventions that include education programs and strategies to improve diet and activity while on the road should be instituted to encourage good habits.

More at Eurekalert.org | Posted 7 years ago by Melody Lesser

Tags: BMI, Columbia University, Diet, Exercise, High Blood Pressure, High Cholesterol, Business Travel

Comment on This | Was this Interesting? Yes! (51%) / No! (49%)

Reduce Inflammation

2 Statin Drugs May Reduce Lung Infection Damage

Sepsis is a serious medical condition and one of the leading causes of hospital death. It is caused when the immune system triggers widespread inflammation, resulting in impaired blood flow, damaging the body’s organs as they are deprived from oxygen and nutrients. Statin drugs, best known for their ability to reduce cholesterol, have been found to play a crucial role in the reduction of lung damage resulting from severe abdominal sepsis and infection. Researchers with Skane University Hospital in Sweden studied the effects of simvastatin on laboratory mice with punctured intestinal bowels. The animals had significantly less lung injury and fewer inflammatory cells than those given a placebo. Each year, severe sepsis strikes about 750,000 Americans and as many as half die.

More at EurekAlert | Posted 7 years ago by Denise Reynolds

Previously: Hospital Infection Rates on the Rise

Tags: Infection, Infections, Sepsis, Septic Shock, Statin, Statins, Statins and Mortality Rate Due to Infections

Comment on This | Was this Interesting? Yes! (46%) / No! (54%)

Works by Inhibiting Same Protein

3 Kidney Cancer Drug May Help Treat Mesothelioma

Scientists in Austria have found that the drug Temsirolimus which has been found to be effective in treating advanced renal cell carcinoma may also slow the growth of pleural mesothelioma cells. Temsirolimus is part of a class of drugs known as protein kinase inhibitors and works by inhibiting rapamycin (mTOR) which is a protein that regulates cell growth. Studies show that the drug not only inhibits the growth of mesothelioma cells but also increased their sensitivity to cisplatin, a drug commonly used in chemotherapy. Pleural mesothelioma is a cancer of the cells lining the lung and is caused by chronic asbestos exposure. Patients’ average survival time is less than a year due to diagnosis at an advanced stage and resistance to multiple types of treatment.

More at Science Daily | Posted 7 years ago by Kristie Hayes

Previously: Kidney Cancer Drug Fights Advanced Thyroid Cancer

Tags: Mesothelioma, Pleural Mesothelioma, Temsirolimus, Protein Kinase Inhibitors, Cisplatin, Treating Mesothelioma, Renal Cell Carcinoma, Rapamycin, MTOR, Cancer Cell Growth

Comment on This | Was this Interesting? Yes! (53%) / No! (47%)

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